不寻常的前后分段特征的外套疾病
Matteo Maria Girolamo1, Theodora Hadjistilianou1, Andrea Lembo2
1Department of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, OcularOncology - Retinoblastoma Referral Center, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
European journal of ophthalmology
|July 13, 2023
概括
科茨病的不寻常特征,如视网膜巨囊和胆固醇症,在幼儿中更为常见. 节的考茨病和瘤在老年患者中更频繁地出现,这表明年龄作为预后标志物.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 儿科眼科医生 儿科眼科医生
背景情况:
- 科茨病是一种罕见的异常性视网膜血管异常,其特征是telangiectasias和排泄.
- 典型的表现包括视网膜排泄物和新血管化,但可能会出现不寻常的临床特征.
- 提高对罕见病情的认识对于及时诊断和管理至关重要.
研究的目的:
- 描述Coats病罕见前后段表现的临床过程和治疗方法.
- 调查患者年龄与这些不寻常的临床特征之间的关系.
- 为了提高识别科茨病在文献中较少报道的方面.
主要方法:
- 对45名患有科茨病的45名患者的45只眼睛进行了回顾性描述性审查.
- 数据是从2000年到2022年在专门的视网母细胞瘤推中心收集的.
- 分析了医疗记录和图像,以确定不寻常的前后段特征.
主要成果:
- 六名患者 (13.3%) 呈现出不寻常的特征:视网膜巨囊 (4.4%),前腔胆固醇化 (2.2%),节节的考茨病 (4.4%),以及相关的血管增殖性瘤 (2.2%).
- 在年幼的儿童中观察到视网膜巨囊和前腔胆固醇症.
- 在老年患者中,可茨病和血管扩散性瘤更为常见.
结论:
- 年龄是科茨病的显著预后标志物,区分表型.
- 年轻的患者 (<3岁) 往往呈现出更具侵略性的疾病,而老年患者 (>3岁) 可能具有较温和的表型.
- 识别这些不寻常的表现及其与年龄相关的患病率可以有助于更好的患者分层和管理.
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