设计和开发光电化学生物传感器件,用于诊断慢性病
Divya1, Darshna1, Aditi Sammi1
1Laboratory of Bio-Physio Sensors and Nanobioengineering School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India.
Biotechnology and bioengineering
|July 13, 2023
概括
早期发现慢性病 (CKD) 是至关重要的. 生物传感器提供了一个有前途的解决方案,用于使用关键生物标志物准确,经济高效地对CKD进行现场诊断.
科学领域:
- 生物医学工程 生物医学工程
- 分析化学 分析化学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 慢性病 (CKD) 是一个日益严重的全球健康问题,预计到2050年将成为第五大死亡原因.
- 早期发现病对于预防严重功能障碍和减少整体疾病负担至关重要.
- 传统的诊断方法面临挑战,突出需要先进的检测解决方案.
研究的目的:
- 审查全球开发的生物传感器用于慢性病 (CKD) 检测.
- 专注于这些生物传感器的设计,模式和现实世界的应用性.
- 将光学和电化学生物传感系统及其性能与关键临床生物标志物进行比较.
主要方法:
- 关于生物传感器用于CKD检测的现有文献的全面审查.
- 详细讨论光学和电化学生物传感器分类.
- 基于白蛋白和肌素等临床生物标志物的生物传感器性能分析.
主要成果:
- 生物传感器为CKD提供了更简单,更具成本效益,更精确的现场检测方法.
- 光学和电化学生物传感器是诊断病的关键技术.
- 各种生物传感器的表格比较,详细说明分析性能,响应时间,特异性和生物流体兼容性.
结论:
- 生物传感器在诊断和预防CKD方面取得了重大进展.
- 该审查为了解CKD当前生物传感器技术提供了宝贵的资源.
- 生物传感器的进一步开发和应用可以提高慢性瘤的早期检测率和患者的治疗结果.
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