准备用于长期起作用的PrEP:在口服PrEP的经验中吸取教训
Connie Celum1, Beatriz Grinsztejn2, Kenneth Ngure3
1Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, Washington, USA.
Journal of the International AIDS Society
|July 13, 2023
概括
长效 (LA) 艾滋病毒暴露前预防 (PrEP) 提供了增加覆盖率和有效性的新选择. 从口服PrEP交付中吸取的经验教训,专注于服务交付和客户支持,对于优化LA PrEP实施至关重要.
科学领域:
- 公共卫生 公共卫生
- 预防传染病 预防传染病
- 艾滋病毒/艾滋病研究研究
背景情况:
- 最近批准的长期 (LA) 艾滋病毒暴露前预防 (PrEP),包括注射性卡博特格拉维尔和达皮维林环,需要优化交付策略.
- 从十年的口服PrEP治疗中吸取经验教训对于成功实施新的LA PrEP方法至关重要.
研究的目的:
- 概述优化提供长效艾滋病毒暴露前预防 (PrEP) 的关键考虑因素.
- 将成功的策略从口服PrEP输送调整为新的长效配方.
- 通过扩大PrEP选项,提高艾滋病毒预防覆盖率,坚持性,持续性和有效性.
主要方法:
- 围绕差异化的服务交付构建块框架LA PrEP交付.
- 确定关键因素:人口覆盖范围,服务位置,减少用户负担和服务集成.
- 整合社区共同发展以创造需求和教育,提供者培训和定制的坚持支持.
主要成果:
- 优化LA PrEP的交付需要战略规划,以实现可访问性,用户便利性和与其他卫生服务的整合.
- 有效的需求创造,明智的客户决策和全面的供应商培训对于成功的采用至关重要.
- 定制的坚持支持和灵活的服务提供模式 (例如,telePrEP,以药房为基础) 对于坚持至关重要.
结论:
- 通过使用LA配方扩大PrEP选择,可以通过满足各种个体需求来增加覆盖率,坚持性,持久性和有效性.
- 关于需求创造,客户参与,提供者教育,坚持支持和服务模式的口服PrEP交付所吸取的经验教训直接适用于LA PrEP实施.
- 综合服务提供模式对于在更广泛的艾滋病毒预防和性健康计划中最大限度地发挥LA PrEP的影响至关重要.
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