考虑和临床管理的感染在类固醇症
Edward S Chen1, Karen C Patterson2
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, Maryland 21224, USA.
Current opinion in pulmonary medicine
|July 13, 2023
概括
患有沙尔科病的患者面临更高的严重感染风险,特别是真菌感染,特别是当免疫抑制时. 然而,对于COVID-19的结果通常不会更糟,除非存在并发症.
科学领域:
- 传染病流行病学 传染病流行病学
- 肺部医学 肺部医学
- 免疫学 免疫学 免疫学
背景情况:
- 与一般人群相比,型硬化症患者患重症感染的风险较高,包括真菌感染.
- 常用于治疗沙尔科病的免疫抑制疗法进一步加剧了感染风险,可能导致住院治疗.
- 虽然COVID-19的严重后果在 Sarcoidosis 患者中并非本质上更高,但先前存在的肺功能障碍和并发病症显著增加了这种风险.
结论:
- 虽然严重的感染在非流行地区相对罕见,但如果错过,它们会造成相当大的负担,这强调了需要仔细监测的必要性.
- 在没有器官功能障碍的情况下, Sarcoidosis 本身似乎不会恶化 COVID-19 的预后,但并发症是关键因素.
- 需要进一步的研究来量化呼吸道病毒病对沙尔科毒症患者生活质量和功能能力的影响.
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