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饮食中微量矿物质的模式影响肠道微生物群和 brojlers的肠道健康
Chuanlong Wang1,2,3, Liangzhi Wang4, Qingyi Chen3
1Mineral Nutrition Research Division, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Journal of animal science
|July 13, 2023
概括
优化饮食中微量矿物质 (铜,铁,,和) 改善肉肠道健康和肠道微生物群. 国家研究委员会 (NRC) 对无机微量矿物质的建议支持更好的肠道形态和有益细菌.
科学领域:
- 动物科学动物科学
- 营养生物化学 营养生物化学
- 微生物学 微生物学
背景情况:
- 饮食中微量矿物质对肠道健康至关重要,影响肠道菌群和肠道完整性.
- 了解微量矿物质 (Cu,Fe,Mn,Zn,Se) 的最佳平衡对于肉肠道健康至关重要.
- 目前对 brojlers 中微量矿物质的饮食建议需要进一步调查它们对肠道健康参数的影响.
研究的目的:
- 为了研究不同饮食模式的铜 (Cu),铁 (Fe), (Mn), (Zn) 和 (Se) 对 brojler肠道形态,微生物群,短链脂肪酸 (SCFA),抗氧化状态和紧结蛋白表达的影响.
- 确定最佳的饮食模式和微量矿物质水平,以改善 brojlers 的肠道健康.
- 为了比较不同补充水平的无机与有机微量矿物质来源的疗效.
主要方法:
- 在Arbor Acres的240只雄性肉被分为五个饮食治疗组,持续42天.
- 处理包括不同水平和来源 (无机/有机) 的Cu,Fe,Mn,Zn和Se,基于NRC,MAP和以前的研究建议.
- 评估了肠道形态 (维卢斯高度,密室深度),乳头微生物群 (香农指数),乳头和乳头SCFA度,抗氧化状态以及乳头/十二指肠紧结蛋白 (Claudin-1,Occludin) mRNA和蛋白质表达.
主要成果:
- 饮食模式T1 (基于NRC建议的无机微量矿物质) 导致了十二指甲骨和甲骨形态的改善,以及乳腺菌在阴茎中的丰度增加.
- 特定的微量矿物质模式影响了脑内微生物群多样性 (香农指数) 和SCFA度 (酸).
- 紧结蛋白 (Claudin-1和Occludin) 的表达是由不同的微量矿物质模式调节的,这表明对肠道屏障功能的影响.
结论:
- 饮食模式的Cu,Fe,Mn,Zn和Se显著影响肉肠道菌群和肠道健康.
- 肉肠道健康的最佳饮食模式涉及特定水平的无机微量矿物质,符合NRC的建议.
- 对于最佳肠道健康的推水平是:12 mg/kg Cu,229 mg/kg Fe,81 mg/kg Mn,78 mg/kg Zn和0.24 mg/kg Se (日期121) 和11 mg/kg Cu,193 mg/kg Fe,80 mg/kg Mn,73 mg/kg Zn和0.22 mg/kg Se (日期2242). 肠道健康的最佳水平是12 mg/kg Cu,229 mg/kg Fe,81 mg/kg Mn,78 mg/kg Zn和0.24 mg/kg Se (日期121) 和11 mg/kg Cu,193 mg/kg Fe,80 mg/kg Mn,73 mg/kg Zn,以及0.22 mg/kg Se (日期2242).
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