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Updated: Jul 23, 2025

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry
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线粒体单双型突变通过恢复 3243A > G 突变的tRNA 中 taurine 修饰来缓解 MELAS 的呼吸缺陷

Saori Ueda1, Mikako Yagi1,2, Ena Tomoda3

  • 1Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Nucleic acids research
|July 13, 2023
PubMed
概括

3243A>G线粒体DNA突变损害了蛋白质合成. 发现第二个突变,3290T>C,可以恢复线粒体功能,并抑制3243A>G突变患者的疾病症状.

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