红细胞分布宽度是对比诱导脏病的炎症预测标志物,在接受皮肤穿透冠状动脉干预的患者中
Muhamad R Abdel Hammed1, Mohammed A Tohamy2, Sherly Z Boshra3
1Department of Internal Medicine and Hematology Unit, Assiut University Hospitals and South Egypt Cancer Institute Bone Marrow Transplantation Unit, Assiut University, Assiut, Egypt.
The Egyptian journal of immunology
|July 13, 2023
概括
高红细胞分布宽度 (RDW) 表明炎症,并且可以预测皮肤穿透冠状动脉干预 (PCI) 患者的对比诱导脏病 (CIN). RDW是PCI后CIN风险评估的简单,可访问的标志物.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床生物标志物 临床生物标志物
背景情况:
- 对比诱导性脏病 (CIN) 是皮肤冠状动脉干预 (PCI) 后的一个常见并发症.
- 红细胞分布宽度 (RDW) 被认为是全血细胞 (CBC) 计数中的炎症生物标志物.
- 升高的RDW与一种促炎状态有关.
研究的目的:
- 研究RDW作为PCI患者中CIN的预测性炎症标记物的实用性.
- 评估RDW水平与CIN发展之间的关联.
主要方法:
- 这是一项前性研究,涉及126名接受PCI的患者.
- 进行了实验室测试,包括CBC,肝功能,HbA1C,脂质概况和血清学测试.
- 血清尿素和肌素水平在基线和PCI后48-72小时被测量以诊断CIN.
主要成果:
- 与没有CIN的患者相比,患有CIN的患者的RDW水平显著更高 (p < 0.001).
- 在非CIN组中观察到更高的血红蛋白水平 (p=0.02).
- 预测CIN的预测因素包括年龄较大,高RDW,升的三角形肌素和对比剂体积.
结论:
- RDW是一种简单,易于获得的炎症生物标志物,可以预测PCI患者中CIN的发展.
- 升高的RDW可以作为CIN风险的早期预警指标.
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