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Updated: Jul 23, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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转载DNA合成聚合酶对基因组稳定性和人类健康的影响

Jegadheeswari Venkadakrishnan1, Ganesh Lahane1, Arti Dhar1

  • 1Department of Pharmacy, Birla Institute of Technology and Sciences Pilani, Hyderabad Campus, Hyderabad, India.

Molecular and cellular biology
|July 13, 2023
PubMed
概括

包括转化合成 (TLS) 聚合酶在内的DNA损伤耐受性 (DDT) 机制,可以防止DNA在复制过程中断裂. 了解TLS对于基因组稳定性和人类健康至关重要,特别是在癌症和化学抵抗方面.

关键词:
造成的DNA损伤是DNA损伤.耐受性 耐受性 耐受性 DNA 损伤这种TLS的聚合物酶.基因组的不稳定性人类疾病 人类疾病转化合成的转化合成

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