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涂抹显微镜对于感染性角膜炎患者治疗决策的有用性
Kaori Mitoma1, Tai-Ichiro Chikama2, Ryotaro Toda2
1Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, 734-8551, Japan. ideguchi@hiroshima-u.ac.jp.
Japanese journal of ophthalmology
|July 13, 2023
概括
涂抹显微镜对于诊断传染性角质炎和指导初始治疗是有用的. 培养对于确认抗菌素敏感性至关重要,理想情况下应该在抗生素治疗之前进行.
科学领域:
- 眼科医生 眼科 眼科
- 微生物学 微生物学
- 诊断微生物学 诊断微生物学
背景情况:
- 传染性角膜炎需要及时诊断和治疗.
- 显微镜检查和培养是标准的诊断方法.
研究的目的:
- 评估涂抹显微镜的诊断实用性,与感染性角膜炎的两种培养方法相比.
主要方法:
- 对73名感染性角膜炎患者的回顾性分析.
- 涂抹显微镜和两种培养技术 (平面介质,擦拭物运输介质) 的比较.
- 评估微生物检测率和方法之间的一致性.
主要成果:
- 在73个标本中的47个标本中检测到微生物.
- 在平面介质上培养的检测率为46.4%,在抽样运输介质上检测率为36.1%.
- 涂抹显微镜和培养结果在28.8%的病例中一致;之前使用抗菌药物减少了检测率.
结论:
- 涂抹显微镜有助于感染性角膜炎的初始治疗.
- 同时培养的研究对于抗菌素敏感性测试至关重要.
- 建议在使用抗菌药物之前进行涂抹显微镜检查.
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