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Updated: Jul 23, 2025

CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.
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CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.

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主编辑策略安装PRPH2 c.828+1G>A 突变

Salvatore Marco Caruso1,2,3, Yi-Ting Tsai1, Bruna Lopes da Costa1,2,3

  • 1Department of Biomedical Engineering, Columbia University, New York, NY, USA.

Advances in experimental medicine and biology
|July 13, 2023
PubMed
概括

周围蛋白2 (PRPH2) 的突变会导致遗传性视网膜疾病. 研究人员开发了一种主要编辑方法,精确地将PRPH2突变插入到干细胞中,用于疾病建模.

关键词:
疾病建模 疾病建模这就是PRPH2的原因.主要编辑主要编辑在 RDS RDS RDS 中.这就是 iPSC 的意义.

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