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纤维细胞和肌纤维细胞软组织瘤:成像频谱和放射病理相关性

Sara Haseli¹, Bahar Mansoori¹, Diana Christensen¹

¹From the Department of Radiology, Division of Musculoskeletal Imaging and Intervention (S.H., A.P., F.S.Z., M.C.), Department of Radiology, Division of Abdominal Imaging (B.M., D.C., A.A.), and Department of Laboratory Medicine and Pathology (B.M.), University of Washington, UW Radiology-Roosevelt Clinic, 4245 Roosevelt Way NE, Box 354755, Seattle, WA 98105; Cancer Immunology Project, Universal Scientific Education and Research Network, Philadelphia, Pa (N.K.); and Department of Radiologic Pathology, Armed Forces Institute of Pathology, Walter Reed Army Medical Center, Washington, DC (M.M.).

Radiographics : a review publication of the Radiological Society of North America, Inc

|July 13, 2023

概括

纤维细胞和肌纤维细胞瘤从良性变为恶性,在儿童中很常见. 图像特征与组织病理学相关,有助于对这些软组织瘤的诊断和治疗计划.

科学领域:

在瘤学瘤学.
放射学放射学是指放射学
病理学病理学病理学

背景情况:

纤维细胞和肌纤维细胞瘤包括一系列瘤,从良性到恶性.
这些瘤经常影响儿童群体,其临床表现因位置和行为而异.
2020年世界卫生组织 (WHO) 的分类系统根据生物行为,组织形态学和分子形状将这些瘤分为四组.

研究的目的:

探索纤维细胞和肌纤维细胞瘤的放射病理相关性.
突出瘤组件的成像检测如何有助于诊断,预后和治疗计划.
强调了解这些相关性对于准确的皮肤透析活检和避免不必要的干预的重要性.

主要方法:

对纤维细胞和肌纤维细胞瘤的成像特征 (例如,T2加权的MR信号强度) 的审查.
图像检测结果与组织病理学变异的相关性 (例如,myxoid矩阵,细胞性,原蛋白含量).
根据2020年世卫组织系统对瘤的分类.

主要成果:

图像特征,如T2加权的MRI图像上的信号强度,可以预测他的病理学变异.
体或体成分与高T2信号强度相关.
超细胞性和密集的原蛋白含量与低T2信号强度相关.

结论:

放射病学相关性对于纤维细胞和肌纤维细胞瘤的准确诊断和管理至关重要.
了解这些相关性可以提高诊断的准确性,并可以指导治疗策略.
这种知识有助于优化穿皮活检程序,防止不必要的干预.

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