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Updated: Jul 23, 2025

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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难以调整内在无序的蛋白质序列的困难,根据保护和分化学来评估

Andrew C Riley1,2, Daniel A Ashlock1,3, Steffen P Graether1,2

  • 1Graduate Program in Bioinformatics, University of Guelph, Guelph, Ontario, Canada.

PloS one
|July 13, 2023
PubMed
概括

内在无序的蛋白质 (IDP) 显示出较少的对齐一致性比有序的蛋白质由于较低的序列保存. 然而,它们的排列仍然准确地重建了物种树,表明质量很好.

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