长期裂的门诊患者注射肉毒素
Şeref Dokcu1, Salim İlksen Başçeken1
1Gazi Yaşargil Training and Research Hospital Surgical Oncology Department, Health Sciences University, Kayapınar Diyarbakır, Turkey.
Acta chirurgica Belgica
|July 13, 2023
概括
毒素 (BT) 注射有效地治疗慢性裂 (CAF) 在门诊环境中,疼痛最小. 大多数患者经历愈合和症状缓解,尽管短暂的失禁是可能的副作用.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
背景情况:
- 慢性裂 (CAF) 是一种常见的疾病,引起显著的疼痛和不适.
- 目前的治疗方法包括局部治疗,肉毒素 (BT) 注射和侧侧内切除术 (LIS).
研究的目的:
- 评估BT注射在没有镇静的门诊环境下对CAF治疗的疗效和安全性.
- 评估术后疼痛,裂愈合率,以及与CAFBT注射相关的并发症.
主要方法:
- 对67名CAF患者的数据进行前性分析,这些患者接受了双边BT注射 (共100个单位) 进入内部关节 (IAS) 的治疗.
- 收集的数据包括人口统计信息,疼痛评分 (VAS),症状改善,愈合率,并发症和随访持续时间.
主要成果:
- 58%的患者在1周内出现了症状改善.
- 在6个月后,观察到82%的完全响应率. 部分响应者 (10%) 和不响应者 (8%) 分别成功地接受了局部治疗或LIS治疗.
- 21%的患者报告过渡性失禁,多次失禁的女性有更多的失禁 (p=0.00). 程序性疼痛是可以容忍的 (VAS中位数为4个前/后,1周后3个).
结论:
- 在无镇静的门诊条件下,BT注射是LIS治疗CAF的有效和安全替代品.
- 应向患者提供咨询,以了解CAF.BT注射后可能出现过渡性失禁的可能性.
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