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在非小细胞肺癌中,PD-L1表达的调节由白蛋白-1β调节

Aiko Hirayama1, Kentaro Tanaka1, Hirono Tsutsumi1

  • 1Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Frontiers in immunology
|July 13, 2023
PubMed
概括

介质素-1β (IL-1β) 和干扰素-γ (IFN-γ) 通过MAPK信号传递,在非小细胞肺癌 (NSCLC) 中协同增加编程细胞死亡连接体1 (PD-L1) 的表达. 准IL-1β-MAPK轴可能会增强抗瘤免疫力.

关键词:
干扰素 - 玛 (IFN-γ) 干扰素介质蛋白-1β (IL-1β) 是一种蛋白质.基因激活蛋白激酶 (MAPK) 途径非小细胞肺癌的肺癌.编程细胞死亡连接物1 (PD-L1)瘤免疫学 瘤免疫学

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