含有毒素mRNA的脂质纳米粒子代表了治疗固体瘤的新策略

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Updated: Jul 27, 2026

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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Yasmin Granot-Matok1,2,3,4, Assaf Ezra1,2,3,4, Srinivas Ramishetti1,2,3,4

  • 1Laboratory of Precision NanoMedicine, Shmunis School for Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

Theranostics
|July 13, 2023
PubMed
概括

修改后的mRNA编码一种细菌毒素,通过脂质纳米颗粒传递,在小鼠模型中显示出显著的抗瘤作用. 这种新的方法为癌症治疗提供了一个有希望的新途径.

关键词:
癌症治疗疗法 癌症治疗基因治疗的基因疗法免疫毒素是一种免疫毒素.脂质纳米颗粒的使用方法它们是mRNARNA.自杀基因疗法 - 自杀基因疗法

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