与轻微缺血性中风不良结果相关的因素
Mai Duy Ton1, Dao Viet Phuong1, Vu Thi Thom2
1Department of Stroke and Cerebrovascular disease, VNU-University of Medicine and Pharmacy, 144 Xuan Thuy, Cau Giay, Hanoi 10000, Vietnam; Stroke Center, Bach Mai hospital, 78 Giai phong road, Phương Mai ward, Dong Da district, Hanoi 10000, Vietnam; Hanoi Medical University, Vietnam.
概括
轻度缺血性中风患者的基线NIHSS为2-4,NIHSS恶化,内动脉狭窄面临较高的不良结果的风险. 早期识别有助于密切监测,以更好地管理中风.
科学领域:
- 神经学 神经学
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 轻度缺血性中风在预防复发和残疾方面存在挑战.
- 识别不利结果的因素对于患者管理至关重要.
研究的目的:
- 确定与轻度缺血性中风患者不良结果相关的因素.
- 确定该患者群体中不良临床结果的预测因素.
主要方法:
- 对轻度缺血性中风患者的前性队列研究 (NIHSS得分≤4).
- 不利的结果定义为修改的兰金度量 (mRS) 2-6 在90天.
- 用于分析风险因素的多变量逻辑回归.
主要成果:
- 基线NIHSS 2-4 (OR,3.85),24小时内NIHSS进展>4 (OR,7.57) 和内动脉狭窄 (ICAS) (OR,1.68) 与不利的结果有关.
- 结果不利的患者基线NIHSS更高,NIHSS进展更大,ICAS的发病率更高.
- 好结果组显示NIHSS得分较低,心血栓事件较少,IV-tPA使用率较低.
结论:
- 基线NIHSS 2-4,NIHSS进展>4在24小时内,ICAS是不利结果的关键预测因素.
- 这些因素有助于识别需要密切监测的高风险患者.
- 这些发现支持针对轻度缺血性中风患者的有针对性的干预措施,这些患者有不良事件的风险.
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