在手术上更换大动脉之后的术后心房动:阿米奥达龙和华法林使用
Brendin R Beaulieu-Jones1, Brenda Lin1, Annette M Phillips2
1Department of Surgery, Boston Medical Center, Boston, Massachusetts; VA Boston Healthcare System, West Roxbury, Massachusetts.
The Journal of surgical research
|July 13, 2023
概括
在进行大动脉置换手术 (SAVR) 后,阿米奥达龙治疗术后心房动 (POAF) 并没有显著影响恢复正常鼻节律 (NSR) 或使用抗凝药. 需要进一步研究节律控制和抗血栓治疗偏好.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术后心房动 (POAF) 是大动脉置换手术 (SAVR) 后的一个常见并发症.
- 在SAVR后的POAF患者中,阿米奥达龙对实现正常的鼻节律 (NSR) 和退院时的抗凝状态的影响尚未得到充分证实.
研究的目的:
- 调查阿米奥达龙治疗与恢复NSR之间的关联.
- 检查SAVR后POAF患者出院时使用阿米奥达龙和抗凝状态之间的关系.
主要方法:
- 在2005-2015年间接受生物SAVR的患者的回顾性分析.
- 用阿米奥达龙治疗的POAF患者与未接受治疗的POAF患者在出院时使用NSR和华法林的比较.
主要成果:
- 在48.0%的患者中发生POAF; 80.1%接受了阿米奥达龙.
- 阿米奥达龙的使用没有显著的差异在回归NSR (70.6%vs65.8%) 或华法林排放 (30.7%vs31.6%).
- 在出院时NSR的患者中,阿米奥达龙治疗没有影响华法林使用 (89.9%对92%).
结论:
- 在SAVR后的POAF中使用阿米奥达龙并没有显著改善回归NSR或影响抗凝决定.
- 外科医生在SAVR后对POAF的节律控制和抗血栓治疗的偏好需要进一步调查.
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