Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Tissues01:18

Tissues

Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
Tissue Membranes01:27

Tissue Membranes

A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial membrane is...
Cells of the Epidermis01:24

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Erratum to PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells.

Cancer biology & medicine·2026
Same author

Interfacial microenvironment engineering in CO<sub>2</sub> electroreduction: mechanisms, advances, and perspectives.

Chemical communications (Cambridge, England)·2026
Same author

Balanced electrochemical reaction kinetics and mass transfer for stable zinc negative electrode.

Nature communications·2026
Same author

Novel models for predicting individualized outcomes in patients with advanced hepatocellular carcinoma receiving immunotherapy.

Frontiers in oncology·2026
Same author

Ethylene (Co)Polymerization Catalyzed by α‑Diimine Nickel Catalysts Bearing Ether Substituents.

Polymer science & technology (Washington, D.C.)·2026
Same author

Molten Salt Assisted Carbon Nitride Overcomes Inherent Photocatalytic Limitations: Unique Characteristics for High-Efficiency Light-Driven Energy Production.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
查看所有相关文章

相关实验视频

Updated: May 13, 2026

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

8.4K

单细胞空间转录组揭示了皮层中的细胞类型组织

Ao Chen1, Yidi Sun2, Ying Lei3

  • 1BGI-Shenzhen, Shenzhen 518103, China; Department of Biology, University of Copenhagen, Copenhagen 2200, Denmark; BGI Research-Southwest, BGI, Chongqing 401329, China; JFL-BGI STOmics Center, Jinfeng Laboratory, Chongqing 401329, China.

Cell
|July 13, 2023
PubMed
概括
此摘要是机器生成的。

研究人员使用先进的测序测绘了大脑皮层中的264种细胞类型. 这个大脑图谱揭示了与大脑层次相关的细胞分布,并确定了灵长类动物特有的细胞类型,有助于未来的神经科学研究.

关键词:
细胞类型组织层次结构的皮层一个细胞空间转录组

更多相关视频

Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing
06:38

Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing

Published on: October 12, 2018

18.9K
Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing DIVA-Seq
07:49

Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing DIVA-Seq

Published on: October 26, 2018

9.5K

相关实验视频

Last Updated: May 13, 2026

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

8.4K
Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing
06:38

Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing

Published on: October 12, 2018

18.9K
Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing DIVA-Seq
07:49

Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing DIVA-Seq

Published on: October 26, 2018

9.5K

科学领域:

  • 神经科学
  • 基因组学
  • 细胞生物学

背景情况:

  • 了解大脑皮层的细胞组织是大脑功能的关键.
  • 之前的研究缺乏细胞类型及其空间分布的全面地图.

研究的目的:

  • 创建一个关于皮细胞类型及其空间组织的详细地图.
  • 研究细胞分布,皮质层次和灵长类细胞类型之间的关系.

主要方法:

  • 大规模的单核RNA测序
  • 在143个皮区域进行空间转录组分析.
  • 跨物种的转录组比较 (人类,,老鼠).

主要成果:

  • 264个转录组定义的皮质细胞类型的综合图谱.
  • 在皮层中绘制细胞类型的空间分布.
  • 在第4层中发现细胞分布,区域层次和灵长类特异性细胞类型之间的联系.

结论:

  • 提供灵长类大脑进化,发育和疾病的细胞和分子基础.
  • 突出了皮层功能中的空间组织的重要性.
  • 识别具有区域依赖基因表达的新型灵长类细胞.