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人类和小鼠早期B细胞发育:如此相似但如此不同

Jakov Korzhenevich1, Iga Janowska2, Mirjam van der Burg3

  • 1Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

Immunology letters
|July 13, 2023
PubMed
概括

本综述比较了人类和小鼠的早期B细胞发育,突出了转录因子和信号通路的关键差异,这些差异对于预测治疗结果至关重要.

关键词:
在B型淋巴发育过程中.骨髓 骨髓 骨髓 骨髓 骨髓细胞因子 (cytokines) 是一种细胞因子.人类 人类 人类 人类 人类鼠标 鼠标是一个鼠标.转录因子 转录因子

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Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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