一般焦虑和分离焦虑对青春期大脑结构发育的不同影响
Zheyi Zhou1, Yiman Li2, Yuqi Zhang2
1State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.
Journal of affective disorders
|July 13, 2023
概括
年轻人焦虑会影响大脑发育. 较高的泛性焦虑和较低的分离焦虑与儿童和青少年脑部结构发育缓慢相关,建议量身定制的治疗方法.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿童和青少年精神病学
背景情况:
- 过度焦虑在儿童和青少年中很常见,会对健康和生活质量产生负面影响.
- 虽然大脑异常与焦虑症有关,但其对大脑发育的影响尚不清楚.
研究的目的:
- 研究焦虑与儿童和青少年大脑结构发育之间的关系.
- 为了确定焦虑是否影响儿童群体的大脑年龄估计.
主要方法:
- 在两个MRI数据集 (733名和775名参与者,年龄在5-18岁) 上使用了多变量分析.
- 通过使用线性支向量的回归来从皮质厚度和表面积预测时间学年龄来估计大脑年龄.
- 对比整个大脑的结构测量与特定的大脑网络进行预测准确性.
主要成果:
- 灰质特征准确地预测了年轻人的年代年龄 (低平均绝对误差).
- 在预测大脑年龄方面,全脑结构测量优于特定网络.
- 增加的泛性焦虑和减少的分离焦虑与较低的大脑年龄有关,这表明大脑发育延迟.
- 父母报告的分居焦虑也与大脑年龄有关.
结论:
- 不同类型的焦虑对儿童和青少年时期的大脑结构发展产生不同的影响.
- 研究结果表明,需要基于年轻人特定焦虑类型的个性化治疗方法.
更多相关视频
10:43Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
Published on: July 1, 2014
15.2K
04:20Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
Published on: July 12, 2024
1.7K
相关概念视频
01:30Generalized Anxiety Disorder
167
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
167
01:28Social Anxiety Disorder
63
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
63
01:18Cognitive Development During Adolescence
81
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
81
03:34Theory of Romantic Attachment in Adulthood
43.5K
Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships.
43.5K
01:14Piaget's Stage 1 of Cognitive Development
669
The sensorimotor stage, the initial phase of Jean Piaget's theory of cognitive development, spans the first two years of a child's life. During this period, infants actively engage with their surroundings, building cognitive awareness through direct interaction with the world. This interaction is primarily based on sensory perception and motor actions, allowing infants to gradually understand basic physical properties and predict how objects interact within their environment.
669
01:29Biological Causes of Schizophrenia
103
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
103