在儿童视网膜母细胞瘤幸存者的视力表征超出视力敏度
Margaret Reynolds1, Jacob Wise1, Tiffany Wu1
1Washington University / Saint Louis Children's Hospital, Saint Louis, Missouri.
概括
接受视网膜母细胞瘤 (RB) 治疗的儿童经常出现对比度敏感性受损和动. 建议对RB幸存者进行全面的视力测试,以确保提供适当的视力康复服务.
科学领域:
- 眼科医生 眼科 眼科
- 儿科瘤学 儿科瘤学
- 视觉科学科学 视觉科学
背景情况:
- 视网母细胞瘤 (RB) 治疗会影响视力敏度,但对对比度敏感性和动的影响还未得到充分研究.
- 有限的数据存在于网膜母细胞瘤幸存者的非急性视觉功能.
研究的目的:
- 在接受视网膜母细胞瘤治疗的儿童中,以表征对比度敏感性和冲刺表现.
- 为了确定与视网膜母细胞瘤幸存者的视力缺陷相关的因素.
主要方法:
- 在11名儿童 (5-17岁) 接受视网膜母细胞瘤治疗后的横截面研究.
- 评估视力敏度,动 (固定分析) 和对比度敏感度 (卡迪夫对比度敏感度).
- 使用多变量线性回归来分析关联.
主要成果:
- 所有完成视觉测试的10名参与者都显示出减弱的曲参数和受损的对比度敏感性.
- 更糟糕的视力敏度和双边疾病与较差的对比度敏感度相关.
- 生殖线疾病与垂直冲刺精度降低有关.
结论:
- 在视网母细胞瘤幸存者中,普遍观察到对比度敏感性下降和失效的萨卡德.
- 建议对所有视网膜母细胞瘤幸存者进行全面的视觉评估.
- 强调需要针对这一群体视力缺陷提供量身定制的康复服务.
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