应用剪切波和磁共振弹性成像来分级脑瘤:系统性审查和元分析
Siddhant Kumarapuram1, Richard Yu1, Pranav Manchiraju1
1Department of Radiology, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA; Department of Neurosurgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
World neurosurgery
|July 13, 2023
概括
磁共振弹性图 (MRE) 和剪波弹性图 (SWE) 显示了对内瘤的分类潜力. 在这个系统性审查中,发现低级瘤比高级瘤更为硬.
科学领域:
- 神经成像是一种神经成像.
- 医学物理 医学物理
- 在瘤学瘤学.
背景情况:
- 磁共振弹性成像 (MRE) 和剪波弹性成像 (SWE) 是测量组织刚性的成像技术.
- 以前的报道表明,MRE和SWE可以根据硬度区分内瘤.
- 需要对现有文献进行系统综合,以证实这些发现.
研究的目的:
- 系统地审查和分析评估SWE和MRE预测脑膜瘤和质瘤瘤等级的能力的研究.
- 评估弹性图谱技术的诊断性能,以对内瘤进行分类.
主要方法:
- 对相关研究进行了PubMed和Scopus的系统搜索.
- 八项涉及176名患者的研究 (84例低级,92例高级瘤) 被纳入了元分析.
- 计算了标准化的硬度平均差异,并使用I2, χ2和t测试来评估异质性. 评估了研究质量和偏见.
主要成果:
- 与高度瘤相比,低度瘤表现出明显更大的硬度 (科恩D=-1.25).
- 观察到最初的中度异质性,但通过对出版年和患者年龄进行控制来减少.
- 包含的研究往往对参考标准和研究流程表现出不清楚或高度偏见.
结论:
- 弹性图像技术,包括MRE和SWE,对手术内和手术后的瘤分级有希望.
- 需要进一步的研究来确定临床效用,并完善这些成像模式用于内瘤的应用.
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