雌激素受体α介导信号抑制I型干扰素反应以促进乳腺癌发生

Li-Bo Cao1,2,3, Zi-Lun Ruan1,2,3, Yu-Lin Yang1,2,3

  • 1Department of Infectious Diseases, Medical Research Institute, Zhongnan Hospital of Wuhan University, College of Life Sciences, Wuhan University, Wuhan 430072, China.

概括

雌激素受体α (ERα) 抑制I型干扰素反应,促进乳腺癌的生长. 用富尔韦斯特兰特阻断ERα可以增强抗瘤效果,这表明了新的治疗策略.

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