从全基因组测序数据中 in silico 预测的 Mycobacterium 结核病 spoligotypes 和 lineages 的比较

Gary Napier1, David Couvin2, Guislaine Refrégier3,4

  • 1Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.

Scientific reports
|July 13, 2023
PubMed
概括

结合型化和全基因组测序 (WGS) 都可以识别Mycobacterium结核病菌株类型. 虽然spoligotyping与主要血统保持一致,但其准确性在更细微的子血统水平上下降,支持其用于监视的用途.

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