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Updated: Jul 23, 2025

An Electrochemiluminescence-Based Assay for MeCP2 Protein Variants
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甲基-CpG结合域2 (Mbd2) 是自闭症风险基因和认知能力的表观遗传调节者

Elad Lax1,2, Sonia Do Carmo3, Yehoshua Enuka4

  • 1Department of Molecular Biology, Ariel University, Ariel, Israel. eladl@ariel.ac.il.

Translational psychiatry
|July 13, 2023
PubMed
概括

在小鼠中,甲基-CpG结合域2 (Mbd2) 损失会损害认知和社会功能. 缺乏mbd2会改变大脑中的基因表达和DNA甲基化,类似于自闭症谱系障碍 (ASD) 的特征.

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