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Updated: Jul 23, 2025

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在USP16和USP36中,ubiquitin/Fubi交叉活性的分子基础是USP16

Rachel O'Dea1,2, Nafizul Kazi1,2, Alicia Hoffmann-Benito1,2

  • 1Chemical Genomics Centre, Max Planck Institute of Molecular Physiology, Dortmund, Germany.

Nature chemical biology
|July 14, 2023
PubMed
概括

研究人员发现,USP16与USP36一起具有双重ubiquitin/Fubi裂变活性,有助于Fubi-S30的成熟. 结构研究揭示了这些二维基因酶的基质识别机制.

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