血管扩大作为在膀癌中节点参与的预测器
Alessandra Borgheresi1,2, Andrea Agostini1,2, Francesca Sternardi2
1Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy.
Diagnostics (Basel, Switzerland)
|July 14, 2023
概括
周围静脉抽血,是淋巴结参与膀癌的迹象,显示高精度. 超过3毫米的最大静脉直径是术前检测淋巴结转移的一个关键指标.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 膀癌 (BC) 淋巴结 (LN) 参与的术前成像缺乏特异性.
- 新血管生成与淋巴扩散有关,这表明可能存在间接成像标记物.
研究的目的:
- 评估周围静脉抽血作为BC.中LN参与的间接迹象.
- 评估传统的CT检测结果与静脉抽血相结合,以改善LN分期.
主要方法:
- 对38名经过彻底囊切除术的BC患者的回顾性分析.
- 术前对比度增强CT (CECT) 通过两台盲读器进行评估.
- 评估LN特征 (形状,,短轴,增强) 和最大静脉直径 (LVD).
主要成果:
- LN短轴> 5毫米,LN增强和LVD> 3毫米与病态N+相关.
- LVD>3mm显示出高的灵敏度和特异性 (≥90%,AUC = 0.949).
- 淋巴结参与的LVD是一个独立的预测因素 (p = 0.0016).
结论:
- 周周静脉切解,特别是LVD> 3毫米,是LN参与膀癌的有价值的间接成像标志物.
- 这一发现可以改善BC患者的手术前分期精度.
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