患者报告结果的工具之间的预测性质的比较:COPD患者未来三次事件的风险预测
Koichi Nishimura1,2, Masaaki Kusunose3, Ryo Sanda3
1Visiting Researcher, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu 474-8511, Japan.
Diagnostics (Basel, Switzerland)
|July 14, 2023
概括
患者报告的结果措施预测了COPD患者的死亡率和恶化. 虽然一些PRO预测死亡率,但FEV1仍然优越;然而,大多数PRO有效预测恶化和住院.
科学领域:
- 肺部医学 肺部医学
- 临床流行病学 临床流行病学
背景情况:
- 患者报告结果 (PRO) 措施对于评估患者健康状况至关重要.
- 它们对慢性阻塞性肺病 (COPD) 临床结果的预测能力需要进一步研究.
研究的目的:
- 评估各种PRO措施对COPD患者全因死亡率,急性恶化和住院治疗的预测性质.
主要方法:
- 122名稳定的COPD门诊患者在基线完成了六个PRO问卷.
- 考克斯的比例危险分析被用来评估与未来死亡率,恶化和住院治疗的关系.
主要成果:
- 几项PRO测量,包括CAT,SGRQ,BDI和海兰尺度,显著预测死亡率.
- 海兰尺度显示了PROs中死亡率的最佳预测能力,尽管低于FEV1.
- 大多数基线PRO,临床和生理测量预测了恶化和住院.
结论:
- 评估健康状况和喘息的PRO测量预测了COPD的死亡率,但FEV1是一个更强的预测因素.
- 意想不到的是,大多数基线PRO强烈预测了COPD患者的恶化和住院.
相关概念视频
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
COPD: Management Using Bronchodilators and Corticosteroids
249
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
249
Chronic Obstructive Pulmonary Disease
1.3K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.3K
Receiver Operating Characteristic Plot
282
A ROC (Receiver Operating Characteristic) plot is a graphical tool used to assess the performance of a binary classification model by illustrating the trade-off between sensitivity (true positive rate) and specificity (false positive rate). By plotting sensitivity against 1 - specificity across various threshold settings, the ROC curve shows how well the model distinguishes between classes, with a curve closer to the top-left corner indicating a more accurate model. The area under the ROC curve...
282
COPD: Pathogenesis and Clinical Features
355
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
355


