膀癌中的基于MRI的放射学:系统性审查和放射学质量评分评估
Bianca Boca1,2, Cosmin Caraiani2, Teodora Telecan3,4
1Department of Radiology, "George Emil Palade", University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.
Diagnostics (Basel, Switzerland)
|July 14, 2023
概括
基于磁共振成像 (MRI) 的放射学显示出膀癌 (BCa) 描述和预后的潜力. 在临床应用这些定量成像生物标志物之前,需要进一步的标准化和验证.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医学成像分析 医学成像分析
背景情况:
- 使用VI-RADS的磁共振成像 (MRI) 是膀癌 (BCa) 阶段的标准.
- VI-RADS有其局限性,包括观察者间的变性和缺乏细胞性信息.
- 放射学提供了一种定量方法来克服这些局限性.
研究的目的:
- 系统地审查基于MRI的放射学研究,以治疗膀癌.
- 评估放射学在BCa分期,分级和治疗反应中的应用.
主要方法:
- 按照PRISMA原则进行系统的文献审查.
- 在PubMed,Scopus和Web of Science中搜索了"膀癌"",磁共振成像"",放射学"和"纹理分析".
- 在1092篇获取的论文中,包括26篇符合条件的研究.
主要成果:
- 放射学主要用于术前瘤分期 (13项研究),等级预测 (9项研究) 和预后/治疗反应 (4项研究).
- 大多数模型使用过图像中的二次特征,并在16项研究中进行了验证.
- 平均放射性质量评分为11.7,具有显著的变化.
结论:
- 基于MRI的放射学显示出作为BCa特征和预后的定量成像生物标志物的前景.
- 图像预处理,特征提取和外部验证的标准化对于临床实施至关重要.
- 需要进一步的研究来完善用于常规临床使用的放射学模型.
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