用扩散张力成像对脑瘤患者白质完整性改变模式的评估:系统性审查
Aiman Abdul Manan1, Noorazrul Azmie Yahya2, Nur Hartini Mohd Taib3,4
1Functional Image Processing Laboratory, Department of Radiology, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Kuala Lumpur 56000, Malaysia.
Cancers
|July 14, 2023
概括
大脑瘤改变白质管道 (WMT) 的完整性,影响大脑组织. 这些微观结构变化的特征有助于瘤诊断,预后和手术规划.
科学领域:
- 神经成像是一种神经成像.
- 神经病理学神经病理学
- 放射学 放射学是一门学科.
背景情况:
- 大脑瘤可以显著影响周围的大脑组织的完整性.
- 了解白质通道 (WMTs) 的变化对于评估瘤影响至关重要.
- 扩散张力成像 (DTI) 提供了对白质微观结构的洞察.
研究的目的:
- 在脑瘤患者中描述白质道微观结构完整性改变的模式.
- 建立评估这些形态和微观结构变化的标准.
- 评估这些变化的诊断和预后价值.
主要方法:
- 按照PRISMA指导方针对Scopus,PubMed/Medline和Web of Science数据库进行系统的文献搜索.
- 选择了25项研究,重点关注脑瘤患者的白质通道完整性.
- 使用通道可视化 (方向,位置) 和DTI参数 (微分异构,明显扩散系数) 来描述WMT变化.
主要成果:
- 没有特定的瘤类型与明显的WMT微观结构变化完全相关.
- 在各种瘤类型和等级中观察到瘤的移位或WMTs的透.
- 形态上的WMT完整性变化提供了有价值的诊断和预后信息.
结论:
- 描述白质管道微观结构完整性的变化对于瘤评估至关重要.
- 这些发现可以帮助早期发现神经系统缺陷和手术决策.
- 基于DTI对WMTs的评估为全面的瘤管理提供了一个潜在的工具.
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