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在细胞癌中超越刀:一个系统的审查 - - 消灭还是不消灭?
Harshani Green1,2, Alexandra Taylor1,2, Vincent Khoo1,2,3,4
1Royal Marsden Hospitals NHS Foundation Trust, London SW3 6JJ, UK.
Cancers
|July 14, 2023
概括
立体体辐射疗法 (SBRT) 显示出对转移性细胞癌 (mRCC) 具有可接受毒性的优秀局部控制. 需要进行更多的研究来比较SBRT与mRCC转移的热除.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 系统治疗的进步改善了转移性细胞癌 (mRCC) 的治疗结果.
- 对于mRCC患者来说,局限转移的局部控制通常是必要的.
- 转移导向的废除疗法提供了局部控制的潜力.
研究的目的:
- 为了评估外mRCC的转移导向的废除疗法.
- 评估立体性身体放射疗法 (SBRT) 和热废除技术的疗效和毒性.
主要方法:
- 按照PRISMA指南进行系统审查.
- 搜索了两个数据库和一个注册表,以查找前性和匹配对病例控制研究.
- 包括针对mRCC的射频剥离 (RFA),冷疗法,微波剥离 (MWA) 和SBRT的研究.
主要成果:
- 确定了18项研究;14项专注于SBRT (424名患者),4项专注于热除 (146名患者).
- 在12个月内,SBRT表现出极好的局部控制率 (LC) (中位数为84.4-87%).
- 平均总生存时间 (OS) 为22.7个月,平均无进展生存时间 (PFS) 为9.3个月;等级≥3毒性范围为1.7%至10%.
结论:
- 立体体辐射疗法 (SBRT) 提供了极好的局部控制和可接受的外mRCC毒性.
- 对热除的有限的合格研究排除了与SBRT的直接比较.
- 需要进一步的最终研究来比较SBRT和热废除技术.
关键词:
在 RCC RCC 里面,你会发现.SABR SABR是一款 SABR 系列的车型.在SBRT和SBRT之间.剥离 剥离 剥离 剥离消耗性疗法是一种消耗性疗法.冰冷疗法 冰冷疗法无线电频率剥离方式细胞癌瘤是细胞癌.立体电磁辐射疗法 立体电磁辐射疗法更多相关视频
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