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相关概念视频

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

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相关实验视频

Updated: Jun 23, 2026

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
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"隐蔽"的前列腺瘤

Vinayak G Wagaskar1, Osama Zaytoun1,2, Swati Bhardwaj3

  • 1Department of Urology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.

Cancers
|July 14, 2023
PubMed
概括
此摘要是机器生成的。

预活检磁共振成像 (MRI) 和系统性前列腺活检 (PBx) 对前列腺癌 (PCa) 检测有显著的错误负率. 需要改进的诊断策略来提高准确性和瘤定位.

关键词:
磁共振成像技术的使用前列腺活检 活检前列腺活检前列腺癌是前列腺癌.

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科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 在瘤学瘤学.
  • 放射学 放射学是一门学科.

背景情况:

  • 前列腺癌 (PCa) 诊断依赖于预剖镜像和活检.
  • 假阴性结果可能导致诊断延迟或错过.

研究的目的:

  • 为了确定预解剖MRI和MRI-超声波 (美国) 引导的12核系统性前列腺活检 (PBx) 的假阴性率.
  • 分析急性前列腺切除样本以评估诊断准确性.

主要方法:

  • 对3600名前列腺癌患者进行了机器人辅助激进前列腺切除术的回顾性分析.
  • 患者根据活检和MRI发现进行了分类:逆侧良性PBx,非可疑的mpMRI,或两者兼而有之.
  • 对PCa,临床显著的PCa (csPCa),外囊延伸 (ECE) 和积极的外科边缘 (PSM) 进行评估.

主要成果:

  • 在各个子组中,PCa检测率各不相同 (19.5%37.7%),其中csPCa检测率从10.3%16.3%不等.
  • 在各子组中,在4-7%的病例中观察到逆侧pT3疾病和积极的外科边缘.

结论:

  • 对于PCa的标准诊断方法显示出显著的虚假阴性率.
  • 进一步的策略是必不可少的,以提高诊断的准确性和精确的瘤定位.