子宫内膜异位症,卵细胞和胚胎质量
Sania Latif1,2, Ertan Saridogan1,2
1Reproductive Medicine Unit, University College London Hospital, London NW1 2BU, UK.
Journal of clinical medicine
|July 14, 2023
概括
子宫内膜异位症会影响卵巢储备和卵细胞质量,但辅助生殖的结果仍然不受影响. 需要进一步的研究来澄清与子宫内膜异位症相关的不孕症的治疗作用.
科学领域:
- 生殖医学 生殖医学
- 妇科 妇科 妇科 妇科
- 不孕症研究 不孕症研究
背景情况:
- 子宫内膜异位症经常在不育妇女中观察到,使她们的不育风险增加了一倍.
- 将子宫内膜异位症与不孕症联系在一起的确切机制尚未完全理解.
- 本综述侧重于子宫内膜异位症对卵细胞和胚胎质量的影响.
研究的目的:
- 评估有关子宫内膜异位症对卵细胞和胚胎质量影响的现有文献.
- 评估与子宫内膜异位症相关的生殖参数变化的临床意义.
- 确定当前研究中的差距,并建议未来的研究方向.
主要方法:
- 关于研究子宫内膜异位症及其对生育能力的影响的综合文献综述.
- 分析来自大型辅助生殖技术 (ART) 登记处的数据.
- 在患有子宫内膜异位症的妇女中评估卵细胞产量,卵细胞质量和胚胎质量.
主要成果:
- 子宫内膜异位症与卵巢储备减少,卵细胞质量和胚胎质量有关.
- 尽管有这些生物效应,但ART注册表显示,对于患有子宫内膜异位症的女性来说,生殖结果没有减少.
- 患有子宫内膜异位症的妇女在ART手术过程中表现出较低的卵细胞产量.
结论:
- 虽然子宫内膜异位症会影响卵细胞和胚胎质量,但其对辅助受精成功的临床影响尚未明确确确立.
- 需要进一步进行精心设计的随机对照试验.
- 在接受辅助怀孕的妇女中,对子宫内膜异位症的手术和医疗治疗的有效性进行调查至关重要.
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