超大胆血症作为创伤患者死亡率和发病率的危险因素
Mina Lee1,2, Myungjin Jang1, Jayun Jo1,2
1Department of Traumatology, Gachon University, Incheon 21565, Republic of Korea.
Journal of clinical medicine
|July 14, 2023
概括
创伤患者的高胆红素水平与肺炎,急性损伤,败血症和伤口感染的风险增加有关. 这项研究发现,高 bilirubinemia 显著与较差的患者结果和较高的死亡率相关.
科学领域:
- 创伤护理 创伤护理
- 关键护理医学 关键护理医学
- 临床生物化学 临床生物化学
背景情况:
- 超白血是创伤患者的常见发现.
- 有限的研究存在于高 bilirubinemia对创伤患者的结果的影响.
- 了解这种关系对于改善患者管理至关重要.
研究的目的:
- 调查严重创伤患者的高 bilirubinemia 和临床结果之间的关联.
- 为了确定升高的胆红素水平是否预测并发症和死亡率.
主要方法:
- 2017年1月至2021年12月期间入院的387名严重创伤患者的回顾性分析.
- 患者被分为低bilirubin (LB,<3 mg/dL) 和高bilirubin (HB,≥3 mg/dL) 的两组.
- 组之间的并发症率 (肺炎,AKI,败血症,伤口感染) 和死亡率的比较.
主要成果:
- 乙型肝炎组的肺炎 (32.3%对10.8%),急性损伤 (AKI) (19.2%对2.8%),败血症 (10.1%对2.8%) 和伤口感染 (30.3%对8.3%) 的发生率明显较高.
- 在HB组中,死亡率也明显高于HB组 (10.1%对4.2%).
- 多变量分析证实,较高的胆红素水平独立增加了这些并发症的风险.
结论:
- 超大胆血是创伤患者不良结果的重要危险因素.
- 升高的胆红素水平与严重创伤后的发病率和死亡率增加有关.
- 创伤患者的临床监测和管理策略应考虑胆红素水平.
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