身体活动对缺血性心脏病死亡率的预后影响:纵向队列研究数据
Dalia Luksiene1, Vilma Jasiukaitiene1, Ricardas Radisauskas1
1Laboratory of Population Studies of Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.
Journal of clinical medicine
|July 14, 2023
概括
定期体育活动显著降低男性缺血性心脏病 (IHD) 死亡风险,无论先前的诊断. 适度的活动对患有IHD的女性有好处.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 越来越多的身体不活动导致全球的非传染性疾病.
- 评估休时间体育活动对缺血性心脏病 (IHD) 死亡率的预后价值至关重要.
- 这项研究基于身体活动水平,按性别和先前的IHD诊断分层地检查了IHD死亡风险.
研究的目的:
- 综合评估休时间体育活动对缺血性心脏病 (IHD) 死亡率的预后价值.
- 要分别分析男性和女性的这些影响.
- 为了区分先前IHD诊断的和没有IHD诊断的个体的结果.
主要方法:
- 在HAPIEE研究 (2006-2008) 中使用了6770名参与者的数据 (年龄在45-72岁之间).
- 休时间的体力活动被量化为每周的小时.
- 对IHD死亡事件的随访发生至2018年12月31日,使用考克斯回归和调解分析.
主要成果:
- 中度和较高的体力活动显著降低了在没有先前IHD的男性中IHD死亡风险 (HR=0.54-0.60).
- 身体活动降低了男性和女性先前患有IHD的IHD死亡风险 (HR=0.41-0.54).
- 调解分析证实,身体活动直接预测了两种性别中较低的IHD死亡率 (p<0.05).
结论:
- 高度体力活动直接预测男性IHD死亡率较低,无论基线IHD状态如何.
- 适度的体力活动是具有IHD病史的女性较低IHD死亡率的重要预测因素.
- 身体活动在不同人群中显示出对IHD死亡率的直接保护作用.
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