相关实验视频
Updated: Jul 23, 2025
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
细胞还原性手术和高温腹腔内化学疗法后的血液学变化
Maria Consuelo Pintado1,2, Inmaculada Lasa Unzúe3, Remedios Gómez Sanz3
1Intensive Care Unit, Hospital Universitario Príncipe de Asturias, 28805 Alcalá de Henares, Spain.
带有高热性腹腔内化疗 (HIPEC) 的细胞还原性手术经常导致血液问题,主要是贫血和白血病. 大多数并发症都是轻微的,并没有影响患者的治疗结果或住院时间.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 密集护理医学 密集护理医学
背景情况:
- 细胞还原性手术 (CRS) 和高热性腹膜内化学疗法 (HIPEC) 是对腹膜转移的既定治疗方法.
- 血液毒性是一种已知的并发症,报告的发病率在2%至38%之间.
研究的目的:
- 调查CRS和HIPEC接受治疗的患者血液学并发症的发生率和特征.
- 评估这些并发症对重症监护室 (ICU) 住院和死亡率的影响.
主要方法:
- 在CRS和HIPEC后入住ICU的96名患者的回顾性分析.
- 收集的数据包括人口统计,癌症类型,HIPEC疗法,血液细胞计数和临床结果.
- 血液学参数,出血事件和输血需求受到特别监测.
主要成果:
- 77.1%的患者出现了血液学并发症,主要是贫血 (66.7%) 和凝血病 (22.9%).
- 白血症在卵巢癌患者或接受多克索鲁比治疗的患者中更为常见.
- 妇女的贫血,特别是卵巢癌或接受西斯普拉丁/多克索鲁比辛治疗的女性,与更长的ICU停留相关.
结论:
- 在CRS和HIPEC之后,大多数血液学并发症并不严重,并自发消失.
- 这些并发症并没有显著影响这一队列的整体死亡率或住院时间.
更多相关视频
09:02Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
13:37A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
Published on: March 12, 2014
相关概念视频
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
01:26Kidney Transplant II: Surgical Procedure