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角膜歇斯底里症中的眼间不对称性与初级开角玻璃眼患者视野严重性的关系

Tadamichi Akagi¹, Yukiho Kato-Takano¹, Daiki Miyamoto¹

¹Division of Ophthalmology and Visual Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.

Journal of clinical medicine

|July 14, 2023

概括

患者眼睛之间的角膜歇斯底里斯 (CH) 大差异与初级开角青光眼 (POAG) 的视野损伤恶化有显著的相关性. 这一发现强调了CH不对称性是POAG进展的关键因素.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
角质生物力学角质生物力学

背景情况:

主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
在POAG患者中,不对称视野损伤很常见.
角膜特性的作用,特别是不对称性,在POAG进展中需要进一步研究.

研究的目的:

调查POAG.患者的非对称角膜歇斯底里症 (CH) 和非对称视野损伤之间的关联.
确定眼间的CH差异是否与视野参数的差异相关.

主要方法:

角膜歇斯底里症 (CH),角膜抵抗因子 (CRF) 和角膜补偿眼内压力 (IOPcc) 在121名POAG患者中使用眼响应分析仪测量.
在各种参数中计算了眼间差异 (DIF_RL和DIF_CH).
标准自动周边测量 (SAP) 24-2和10-2平均偏差 (MD) 用于评估视野损伤.

主要成果:

较低的CH和CRF显着与视野MD的恶化有关.
在SAP24-2 MD中,轴长度的眼间不对称性,IOPcc和CH与眼间不对称性有显著的关联.
患有较大的眼间CH不对称的患者在CRF,IOPcc,CCT和视野MD中表现出显著的差异.

结论:

在角膜歇斯底里症中显著的眼间不对称是解释POAG疾病恶化的关键因素.
角膜的生物力学特性,特别是它们的不对称性,应在POAG的管理中考虑.
进一步研究眼中CH不对称的临床影响是有必要的.

关键词:

中央角膜的厚度角膜的厚度角膜歇斯底里症角膜歇斯底里角膜阻力因子角膜阻力因子眼睛之间的不对称性.主要的开放角光眼 (Glaucoma)

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