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在2型糖尿病中六年内移动性变化的基于组的轨迹建模:弗里曼特尔糖尿病研究II期:弗里曼特尔糖尿病研究II期
David G Bruce1, Wendy A Davis1, Timothy M E Davis1
1Medical School, The University of Western Australia, Fremantle Hospital, Alma Street, Fremantle, WA 6160, Australia.
Journal of clinical medicine
|July 14, 2023
概括
运动障碍在患有2型糖尿病的成年人中是常见的和持久的. 定时升级和移动 (TUG) 测试揭示了近四分之一的个人在六年内持续存在的移动问题.
科学领域:
- 老年学是一门学科.
- 内分泌学 在内分泌学.
- 生物医学工程 生物医学工程
背景情况:
- 移动性对于老年人的独立性至关重要.
- 2型糖尿病与运动能力下降的风险增加有关.
- 关于2型糖尿病运动变化的纵向数据有限.
研究的目的:
- 分析2型糖尿病社区居民的时间移动性变化.
- 使用定时启动和启动 (TUG) 测试来识别不同的移动轨迹.
- 确定与不同移动模式相关的因素.
主要方法:
- 弗里曼特尔糖尿病研究II期 (FDS2) 数据的分析.
- 两年一度的时间和时间 (TUG) 测试超过六年.
- 基于组的轨迹建模 (GBTM) 来识别移动群体.
- 多项式回归用于评估群体成员资格的预测因素.
主要成果:
- 确定了两个稳定的移动性轨迹组 (76.2%和19.4%的参与者).
- 第三组 (4.5%) 显示 TUG 时间增加,然后下降,可能是由于磨损.
- 运动速度较慢的群体年龄较大,更有可能是女性,肥胖,糖尿病并发症较多.
- 近25%的队列在六年内表现出持续或恶化的运动障碍.
结论:
- 在2型糖尿病中,临床相关的运动障碍是普遍和持久的.
- 这种人群的流动性下降是多因素的.
- 定时启动和启动 (TUG) 测试对于评估移动性及其对2型糖尿病的影响具有临床实用性.
- 持久的流动性问题与更高的脱学率和死亡率有关.
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