周围冷却对上肢震严重程度和MS患者的功能能力的影响
Peter Feys1,2, Marijke Duportail3, Daphne Kos3,4
1REVAL Rehabilitation Research Center, Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, 3590 Diepenbeek, Belgium.
Journal of clinical medicine
|July 14, 2023
概括
在患有多发性硬化症 (pwMS) 的人群中,外围上肢冷却显著降低了震的严重程度,并改善了功能表现. 这些好处在冷却后立即观察到,并持续至少25分钟.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 生物医学工程 生物医学工程
背景情况:
- 在患有多发性硬化症 (pwMS) 的人群中,上肢意图震显著影响日常活动.
- 在pwMS中对震的有效治疗方法有限,需要新的治疗方法.
研究的目的:
- 调查外周上肢冷却对pwMS震严重程度和功能表现的影响.
- 为了确定冷却干预后减和功能改善的持续时间和程度.
主要方法:
- 进行了两项实验,涉及在 pwMS 中冷却前臂或整个手臂,并进行意图震.
- 功能性评估包括TEMPA (Test Evaluant les Membres supérieurs des Personnes Agées),法恩的震评分表 (FTRS) 和九洞测试 (NHPT) 等.
- 在冷却干预之前和之后,在多个时间点评估震严重程度和功能表现.
主要成果:
- 前臂冷却显著降低了FTRS分数,提高了NHPT性能,并提高了TEMPA任务的完成.
- 全臂冷却还导致FTRS得分降低,并提高了特定TEMPA任务的性能.
- 观察到的震和功能改善发生在冷却后立即,并持续至少25分钟.
结论:
- 周围上肢冷却是一种有前途的非侵入性干预措施,用于管理 pwMS.
- 冷却干预措施提供了临床上可见的震严重程度的降低和功能能力的改善.
- 冷却的积极影响是立即和持续的,为改善 pwMS 患者的生活质量提供了潜在的治疗策略.
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