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Updated: Jul 23, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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药物遗传学引导的阿片类药物治疗改善慢性疼痛结果和并发性精神健康:一项随机,双盲,受控研究

Laura Agulló1,2, Isidro Aguado1, Javier Muriel1,2

  • 1Pharmacogenetic Unit, Clinical Pharmacology Department, Alicante Institute for Health and Biomedical Research (ISABIAL), General University Hospital of Alicante, c/Pintor Baeza, 12, 03010 Alicante, Spain.

International journal of molecular sciences
|July 14, 2023
PubMed
概括

药物遗传学引导的阿片类药物处方改善了慢性疼痛患者的疼痛缓解和生活质量. 与常规护理相比,基因型导向治疗减少了疼痛强度,不良事件和阿片类药物剂量.

关键词:
科姆特 (COMT) 是一个有价值的项目.在CYP2D6中.在OPRM1中使用OPRM.慢性疼痛是一种慢性疼痛.在阿片类药物阿片类药物.药物遗传学 药物遗传学

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