自然抗氧化剂对健康的影响
1Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
International journal of molecular sciences
|July 14, 2023
概括
自由基是新陈代谢的副产品,导致氧化应激和细胞衰老. 这一过程有助于人体中许多疾病的发展.
科学领域:
- 生物化学 生物化学
- 细胞生物学 细胞生物学
- 人体生理学 人体生理学
背景情况:
- 代谢过程产生自由基.
- 自由基诱导氧化压力.
- 氧化应激与衰老和疾病有关.
研究的目的:
- 解释自由基在人类健康中的作用.
- 突出自由基与疾病病原体之间的联系.
主要方法:
- 关于自由基代谢的文献综述.
- 对参与氧化应激的生物化学途径的分析.
- 氧化应激标志物与疾病发展之间的相关性研究.
主要成果:
- 代谢过程是内源性自由基的主要来源.
- 在高氧化应激和细胞衰老之间观察到显著的相关性.
- 自由基引起的损伤与各种慢性疾病有关.
结论:
- 自由基是氧化应激的关键媒介.
- 管理自由基的产生可以预防与年龄相关的疾病.
- 对抗氧化剂疗法的进一步研究是有必要的.
相关概念视频
Radical Autoxidation
2.2K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.2K
Vitamins
802
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
802
Oxidation of Phenols to Quinones
3.2K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
3.2K
Lifestyle Factors and Health
84
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
84
Effects of Chemicals: Overview
1.3K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
1.3K
Aging
89
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
89


