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Updated: Jul 23, 2025

Bio-layer Interferometry for Measuring Kinetics of Protein-protein Interactions and Allosteric Ligand Effects
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Bio-layer Interferometry for Measuring Kinetics of Protein-protein Interactions and Allosteric Ligand Effects

Published on: February 18, 2014

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分子动力学模拟与马尔科夫模型相结合,探索菌抑制剂对含odomain蛋白4的结合效应

Xiaotang Yang1, Yilin Gao1, Fuyan Cao1

  • 1Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, 2699 Qianjin Street, Changchun 130012, China.

International journal of molecular sciences
|July 14, 2023
PubMed
概括

这项研究揭示了全抑制剂ZL0590如何作用于含有odomain的蛋白4 (BRD4). ZL0590改变了BRD4的情况

关键词:
含有原体的蛋白质4 (BRD4)马尔科夫模型的模型全osteric调节的调节.形状的变化 形状的变化分子动力学模拟,分子动力学模拟

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