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Updated: Jul 23, 2025

Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
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Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators

Published on: November 27, 2015

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通过使用离子液体,获得基纯克洛皮多格勒的生物方法

Joanna Chałupka1, Adam Sikora1, Marta Ziegler-Borowska2

  • 1Department of Medicinal Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Dr. A. Jurasza 2, 85-089 Bydgoszcz, Poland.

International journal of molecular sciences
|July 14, 2023
PubMed
概括

这项研究成功地产生了 (S) - 克洛皮多格勒,一种抗血小板药物,使用在离子液体介质中皮多格勒碳酸酸的脂酶催化动态分辨率. 这种绿色化学方法提供了一种有效的方法来获得所需的反体.

关键词:
在Candida rugosa中使用.克洛皮多格雷尔的使用方法通过对抗选择性生物转化.离子液体是一种离子液体.脂酶脂酶的使用方法

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