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低密度脂蛋白受体是甲状腺瘤细胞侵略性的关键驱动因素

Giovanna Revilla1,2, Lara Ruiz-Auladell1, Núria Fucui Vallverdú1

  • 1Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica (IIB) Sant Pau, 08041 Barcelona, Spain.

International journal of molecular sciences
|July 14, 2023
PubMed
概括

低密度脂蛋白 (LDL) 可以通过调节LDL受体 (LDLR) 和MAPK通路来加速乳头甲状腺癌 (PTC) 的攻击性,特别是在BRAF V600E突变细胞中. 向LDLR提供了一个潜在的治疗策略,用于攻击性的PTC.

关键词:
在BRAF V600E中使用.在RAS/RAF/MAPK (MEK) /ERK路径中.低密度脂蛋白 (LDL) 是一种低密度脂蛋白.低密度脂蛋白受体 (LDLR) 是一种低密度脂蛋白受体.甲状腺癌 (TC) 是一种

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