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Updated: Jul 23, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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迪亚里尔-皮拉诺-克罗门亚特罗皮索默:立体动力学和合规研究

Alessia Ciogli1, Andrea Fochetti1, Andrea Sorato1

  • 1Department of Chemistry and Drug Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Roma, Italy.

Molecules (Basel, Switzerland)
|July 14, 2023
PubMed
概括

迪-阿里尔-皮拉诺-染色体表现出动态的行为,由于它们的结构,形成同/反二异构体和构造性反体. 研究人员使用计算和实验方法来确定旋转障碍,并分配绝对配置.

关键词:
在 DFT 方面,它是最重要的.动态-HPLC 的动态.动态-NMR是一种动态的NMR.在ECD中,我们可以使用ECD.这是TD-DFTT.阿里尔斯 - 皮拉诺 - 克罗米内斯它们是基性基聚合物.

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