酸从综合性聚钢主干纤维中释放的酸
Verdiana Covelli1,2, Antonietta Cozzolino1, Paola Rizzo1
1Department of Chemistry and Biology "A. Zambelli" and INSTM Research Unit, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.
Molecules (Basel, Switzerland)
|July 14, 2023
概括
装有酸 (SA) 的综合性多聚烯 (sPS) 纤维可以定制为抗菌应用. sPS纤维的不同晶体相控制SA释放,使其在织品,食品和公共卫生中使用成为可能.
科学领域:
- 材料科学 材料科学 材料科学
- 聚合物科学 聚合物科学
- 生物材料是一种生物材料.
背景情况:
- 合成聚乙烯 (sPS) 是一种具有无形和晶体相的多功能聚合物.
- 酸 (SA) 是一种非挥发性抗微生物分子,在各种领域都有潜在的应用.
- 从聚合物矩阵中控制抗菌剂的释放动力学对于有效的应用至关重要.
研究的目的:
- 为了表征综合性质的聚钢 (sPS) /酸 (SA) 共同晶体 (CC) δ形式.
- 研究装有SA.的sPS纤维的制备和特性.
- 评估具有不同晶相的sPS纤维在抗微生物应用中的潜力.
主要方法:
- 广角X射线衍射 (WAXD) 和极化里叶变换红外光谱 (FTIR) 用于表征.
- 用不同的SA负载和晶体相准备sPS纤维.
- 进行了基于细胞的测定和抗菌试验,以评估SA释放,活性和毒性.
主要成果:
- 成功形成了sPS/SA δ CC相,允许高SA负载和保持在纤维中,即使在洗后.
- 从无形纤维开始的制备方法产生了直接的CC δ形状形成和轴向.
- 具有 δ CC 形式的纤维显示保留了适用于抗微生物织品的 SA,而 γ 形式的纤维释放了用于食品和公共卫生应用的 SA.
结论:
- 可以调节sPS纤维的晶相,以控制SA加载和释放动力学.
- 装有SA的sPS纤维为各种应用提供可调节的抗微生物特性,包括织品,食品保存和公共卫生.
- 这项研究表明sPS纤维的潜力,作为开发有效的基于SA的抗菌材料的平台.
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