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Updated: Jul 23, 2025

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
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一种氨酸 - 胺基二甲衍生物,SP11通过向HSP90及其客户端蛋白质来抑制瘤生长

Snehal Nirgude1,2, Shahana M V1, Febina Ravindran1

  • 1Institute of Bioinformatics and Applied Biotechnology, Electronic City Phase 1, Bangalore 560100, Karnataka, India.

Molecules (Basel, Switzerland)
|July 14, 2023
PubMed
概括

一种新型的HSP90抑制剂SP11有效地向白血病和淋巴瘤细胞,以最小的毒性诱导亡. 这种药物通过在临床前模型中减少瘤负担,显示出作为一种新的血液癌症治疗的前景.

关键词:
DLA小鼠瘤模型的模型.这是一种HSP90抑制剂.抗癌治疗药物 抗癌治疗药物灭症 (apoptosis) 是一种死亡的过程.

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