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含有 β-环极的复合物与Salvia officinalis生物活性化合物及其抗菌活性

Stamatia Christaki¹, Revekka Kelesidou¹, Vaia Pargana¹

¹Department of Food Science and Technology, School of Agriculture, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.

Plants (Basel, Switzerland)

|July 14, 2023

概括

圣精油 (SEO) 与β-cyclodextrin (β-CD) 形成有效的包括综合体. 这些复合物对Listeria monocytogenes和Staphylococcus aureus表现出抗菌活性,其有效性随着度的增加而增加.

科学领域:

自然产品化学自然产品化学
材料科学材料科学材料科学
微生物学微生物学

背景情况:

(Salvia officinalis) 含有具有潜在治疗应用的生物活性化合物.
β-cyclodextrin (β-CD) 是一种循环寡糖,以其与各种分子形成包容复合物的能力而闻名.
精油的封装可以提高其稳定性和生物可用性.

研究的目的:

研究精油 (SEO) 生物活性化合物和β-CD.之间的分子包容复合物的形成.
为了描述SEO/β-CD纳入复合体.
为了评估SEO/β-CD纳入复合物的抗菌疗效.

主要方法:

通过共同沉来准备SEO/β-CD纳入复合体.
福里埃变换红外光谱法 (FT-IR) 用于复杂的表征.
在综合体内的SEO的光谱光度量化.
针对大肠杆菌,金黄色葡萄球菌和单细胞杆菌李斯特菌的抗菌检测.

主要成果:

证实了SEO/β-CD纳入复合物的成功形成.
β-CD有效地将SEO封装在令人满意的产量中.
该SEO/β-CD纳入复合体显示了针对L. monocytogenes和S. aureus的抗菌活性.
与免费SEO相比,抗微生物活性依赖于度,但较少明显.

结论:

β-CD是一种有效的宿主,可以与精油形成含有复合体.
开发的纳入复合物显示出抗微生物应用的潜力.
进一步的研究可能会优化复杂化以提高生物活性.

关键词:

在FT-IR中,使用的是FT-IR.它具有抗菌活性,具有抗菌活性.包容性复杂的包容性复杂的植物化学植物化学智慧的智慧的智慧的智慧的智慧的智慧这是一种β-cyclodextrin.

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