饮食炎症指数与胃腺癌之间的关联:巴西的一项多中心病例控制研究
Alex Richard Costa Silva1, Valdete Regina Guandalini2,3, Taísa Sabrina Silva Pereira4
1Postgraduate Program in Oncology, A.C. Camargo Cancer Center, São Paulo 01509-900, Brazil.
Nutrients
|July 14, 2023
概括
通过更高的能量调整的饮食炎症指数 (E-DII) 评分来衡量的促炎症饮食与巴西胃腺癌 (GA) 风险增加有关. 这一发现凸显了饮食模式在GA发展中的重要性.
科学领域:
- 胃肠道学和瘤学
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
背景情况:
- 在巴西,关于饮食炎症和胃腺癌 (GA) 的研究有限.
- 这项研究调查了巴西人口中促炎饮食和GA风险之间的关联.
研究的目的:
- 评估促炎性饮食与胃腺癌 (GA) 风险之间的关联.
- 检查不同GA亚型和对照组之间的这种关联.
主要方法:
- 在巴西进行了一项多中心病例控制研究,涉及1645名参与者.
- 能量调整的饮食炎症指数 (E-DII) 得分是从食物频率问卷中计算出来的.
- 后勤回归模型分析了E-DII得分与GA风险之间的关联,包括亚型.
主要成果:
- 较高的E-DII得分 (促炎饮食) 在两种病例对照比较中都与增加的GA风险有关.
- 促炎症饮食与非心脏GA和扩散组织学亚型的更高风险有关.
- 根据使用的对照组观察到心脏,非心脏,肠道和扩散GA亚型的关联.
结论:
- 这项研究提供了证据,将促炎症饮食与巴西胃腺癌风险增加联系起来.
- 这些发现表明,在GA预防策略中需要考虑饮食因素,包括.
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