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优化的薄荷精油微囊装入基于凝的冷凝,具有增强的抗菌活性

Didem Demir¹, Gulden Goksen², Seda Ceylan³

¹Department of Chemistry and Chemical Process Technologies, Vocational School of Technical Sciences at Mersin Tarsus Organized Industrial Zone, Tarsus University, Mersin 33100, Türkiye.

|July 14, 2023

概括

胡卜精油 (PEO) 微封装的胡卜精油 (PEO) 在一种新的凝冷凝中. 这种增强的PEO输送系统表现出卓越的抗菌活性,并改善了各种应用的结构性质.

科学领域:

生物材料科学生物材料科学
材料化学材料化学
纳米技术纳米技术

背景情况:

薄荷精油 (PEO) 具有宝贵的抗菌特性,但在稳定性和受控释放方面面临挑战.
微封装技术对于保护挥发性化合物和增强其功能至关重要.
基于凝的冷凝由于其独特的多孔结构,为生物材料开发提供了多功能支架.

研究的目的:

开发和描述一种新的基于凝的冷凝系统,其中包含素和微封装薄荷精油 (PEO@ChiCap).
评估开发的冷凝系统的形态,物理和抗菌性质.
为了比较冷凝网络内的封装PEO与自由PEO的疗效.

主要方法:

酸盐 (Chi) 用于微封装PEO.
制造了四种不同的基于凝的冷凝系统,包括控制系统和使用PEO@ChiCap.Cap的系统.
鉴定包括评估形态 (多孔性),分子,物理 (胀,接触角度) 和抗菌性质.

主要成果:

冰冷凝表现出高度多孔的形态,GelCryo-ChiCap和GelCryo-PEO@ChiCap显示出最高的平衡膨胀比率.
凝Cryo-PEO@ChiCap样本显示较低的接触角度,表明由于PEO而改善的湿透性.
与自由的PEO相比,在冷凝网络中的封装PEO显示出明显增强的抗菌活性,对抗*金黄色葡萄球菌*和*大肠杆菌*.

结论:

开发的GelCryo-PEO@ChiCap系统为稳定和提供PEO提供了一种有效的策略,增强其抗菌功效.
冰凝的结构和PEO的微封装协同改善材料特性和抗菌性能.
这种带有PEO加载的冷凝系统显示出在药物输送,组织工程和食品包装方面的应用潜力显著.

关键词:

它是一种抗菌药物,具有抗菌作用.基多酸盐的使用方法冰冷凝土是用来冷的.这是一种凝凝.微囊微囊是一种微囊.胡薄荷精油胡薄荷精油

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